Publications

We asked that our work be acknowledged in publications and presentations supported by BiNGS.

Group, P.T.C., Calabrese, C., Davidson, N.R., Demircioglu, D., Fonseca, N.A., He, Y., Kahles, A., Lehmann, K.V., Liu, F., Shiraishi, Y., et al. (2020). Genomic basis for RNA alterations in cancer. Nature 578, 129-136.

Han, B.Y., Seah, M.K.Y., Brooks, I.R., Quek, D.H.P., Huxley, D.R., Foo, C.S., Lee, L.T., Wollmann, H., Guo, H., Messerschmidt, D.M., et al. (2020). Global translation during early development depends on the essential transcription factor PRDM10. Nat Commun 11, 3603.

Mzoughi, S., Fong, J.Y., Papadopoli, D., Koh, C.M., Hulea, L., Pigini, P., Di Tullio, F., Andreacchio, G., Hoppe, M.M., Wollmann, H., et al. (2020b). PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis. Nat Commun 11, 3520.

Chung, V.Y., Tan, T.Z., Ye, J., Huang, R.L., Lai, H.C., Kappei, D., Wollmann, H., Guccione, E., and Huang, R.Y. (2019). The role of GRHL2 and epigenetic remodeling in epithelial-mesenchymal plasticity in ovarian cancer cells. Commun Biol 2, 272.

Demircioglu, D., Cukuroglu, E., Kindermans, M., Nandi, T., Calabrese, C., Fonseca, N.A., Kahles, A., Lehmann, K.V., Stegle, O., Brazma, A., et al. (2019). A Pan-cancer Transcriptome Analysis Reveals Pervasive Regulation through Alternative Promoters. Cell 178, 1465-1477 e1417.

Fong, J.Y., Pignata, L., Goy, P.A., Kawabata, K.C., Lee, S.C., Koh, C.M., Musiani, D., Massignani, E., Kotini, A.G., Penson, A., et al. (2019). Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation. Cancer Cell 36, 194-209 e199.

Pobbati, A.V., Mejuch, T., Chakraborty, S., Karatas, H., Bharath, S.R., Gueret, S.M., Goy, P.A., Hahne, G., Pahl, A., Sievers, S., et al. (2019). Identification of Quinolinols as Activators of TEAD-Dependent Transcription. ACS Chem Biol 14, 2909-2921.

Qadeer, Z.A., Valle-Garcia, D., Hasson, D., Sun, Z., Cook, A., Nguyen, C., Soriano, A., Ma, A., Griffiths, L.M., Zeineldin, M., et al. (2019). ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures. Cancer Cell 36, 512-527 e519.

Seah, M.K.Y., Wang, Y., Goy, P.A., Loh, H.M., Peh, W.J., Low, D.H.P., Han, B.Y., Wong, E., Leong, E.L., Wolf, G., et al. (2019). The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons. Development 146.

Steinbach, N., Hasson, D., Mathur, D., Stratikopoulos, E.E., Sachidanandam, R., Bernstein, E., and Parsons, R.E. (2019). PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription. Nucleic Acids Res 47, 5573-5586.

Wang, S., Zhang, C., Hasson, D., Desai, A., SenBanerjee, S., Magnani, E., Ukomadu, C., Lujambio, A., Bernstein, E., and Sadler, K.C. (2019). Epigenetic Compensation Promotes Liver Regeneration. Dev Cell 50, 43-56 e46.

Yu, J.X., Craig, A.J., Duffy, M.E., Villacorta-Martin, C., Miguela, V., Ruiz de Galarreta, M., Scopton, A.P., Silber, L., Maldonado, A.Y., Rialdi, A., et al. (2019). Phenotype-Based Screens with Conformation-Specific Inhibitors Reveal p38 Gamma and Delta as Targets for HCC Polypharmacology. Mol Cancer Ther 18, 1506-1519.

Alonso, A., Bernstein, E., and Hasson, D. (2018). Histone Native Chromatin Immunoprecipitation. Methods Mol Biol 1832, 77-104.

Georgilis, A., Klotz, S., Hanley, C.J., Herranz, N., Weirich, B., Morancho, B., Leote, A.C., D’Artista, L., Gallage, S., Seehawer, M., et al. (2018). PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells. Cancer Cell 34, 85-102 e109.

Strub, T., Ghiraldini, F.G., Carcamo, S., Li, M., Wroblewska, A., Singh, R., Goldberg, M.S., Hasson, D., Wang, Z., Gallagher, S.J., et al. (2018). SIRT6 haploinsufficiency induces BRAF(V600E) melanoma cell resistance to MAPK inhibitors via IGF signalling. Nat Commun 9, 3440.

Tabaglio, T., Low, D.H., Teo, W.K.L., Goy, P.A., Cywoniuk, P., Wollmann, H., Ho, J., Tan, D., Aw, J., Pavesi, A., et al. (2018). MBNL1 alternative splicing isoforms play opposing roles in cancer. Life Sci Alliance 1, e201800157.